Figure 9. Immunoblots of cortical and inner medullary kidney homogenates of mice treated without (con) or with lithium chloride (Li) for 8 days.

A, the expression of aquaporin (AQP)2, AQP3, sodium/calcium exchanger 1 (NCX1), pendrin and actin was determined in cortical kidney homogenates from either wild-type (WT) or AQP2-connecting tubule (CNT)-knockout (KO) mice (KO). B, the expression of AQP2, AQP3 and actin was determined in inner medullary kidney homogenates from the same animals. Data are band densities relative to WT (mean ± SEM) after normalization to actin expression. n= 6 in each group. *P < 0.05.