Table 3.
Major life events and risk of myocardial infarction and ischaemic stroke
| Major life events, sum (with 0 as reference) | Childhood
|
Adulthood
|
||||
|---|---|---|---|---|---|---|
| 1 | > 1 | P value* | 1 | > 1 | P value* | |
| Myocardial infarction | ||||||
| HR (95%) | 1.13 (0.90–1.41)a | 1.13 (0.87–1.47) | 0.29 | 1.03 (0.79–1.33) | 1.05 (0.79–1.39) | 0.73 |
| 1.07 (0.85–1.34)b | 1.02 (0.78–1.34) | 0.77 | 1.01 (0.78–1.31) | 0.95 (0.71–1.27) | 0.74 | |
| 1.12 (0.89–1.41)c | 1.06 (0.80–1.41) | 0.54 | 0.99 (0.75–1.30) | 1.07 (0.80–1.44) | 0.68 | |
| 1.05 (0.83–1.33)d | 0.97 (0.73–1.29) | 0.97 | 1.03 (0.77–1.36) | 1.08 (0.79–1.48) | 0.63 | |
| Ischaemic stroke | ||||||
| HR (95%) | 0.96 (0.73–1.26)a | 1.41 (1.06–1.90) | 0.06 | 1.09 (0.80–1.48) | 1.48 (1.08–2.02) | 0.02 |
| 0.88 (0.67–1.17)b | 1.28 (0.94–1.73) | 0.25 | 1.06 (0.78–1.44) | 1.32 (0.95–1.83) | 0.10 | |
| 0.94 (0.71–1.24)c | 1.36 (1.01–1.83) | 0.11 | 1.10 (0.80–1.50) | 1.53 (1.11–2.10) | 0.01 | |
| 0.86 (0.64–1.16)d | 1.23 (0.90–1.68) | 0.38 | 1.05 (0.76–1.45) | 1.39 (0.99–1.96) | 0.06 | |
HR, hazard ratio.
Adjusted for age and sex.
Adjusted for age, sex and vital exhaustion.
Adjusted for age, sex and traditional risk factors: smoking, diabetes, physical activity, blood pressure and cholesterol-lowering drugs, systolic blood pressure, body mass index, atrial fibrillation and blood lipids. Alcohol consumption, hormone replacement therapy, familiar disposition and blood glucose were not associated with stroke or myocardial infarction in this study sample.
Adjusted for age, sex, vital exhaustion, traditional and socioeconomic risk factors: cohabitation, education and household income. Employment was not associated with stroke or myocardial infarction in this study sample.
P value for test for trend.