Table 4.
MLEs in a life course and risk of myocardial infarction and ischaemic stroke
| MLEs, sum (with 0 as reference) | MLE in a life course
|
|||
|---|---|---|---|---|
| 1–2 | 3–4 | > 4 | P value* | |
| Myocardial infarction | ||||
| HR (95%) | 1.31 (0.98–1.73)a | 1.45 (1.04–2.03) | 0.72 (0.40–1.28) | 0.65 |
| 1.23 (0.92–1.64)b | 1.27 (0.90–1.80) | 0.61 (0.34–1.09) | 0.64 | |
| 1.36 (1.01–1.85)c | 1.43 (1.00–2.05) | 0.81 (0.44–1.50) | 0.54 | |
| 1.34 (0.98–1.82)d | 1.38 (0.95–2.01) | 0.76 (0.41–1.41) | 0.74 | |
| Ischaemic stroke | ||||
| HR (95%) | 1.06 (0.77–1.46)a | 1.26 (0.86–1.86) | 1.53 (0.93–2.52) | 0.07 |
| 1.00 (0.72–1.39)b | 1.14 (0.76–1.69) | 1.31 (0.79–2.20) | 0.27 | |
| 1.07 (0.77–1.48)c | 1.25 (0.84–1.85) | 1.57 (0.94–2.61) | 0.07 | |
| 0.99 (0.71–1.39)d | 1.17 (0.78–1.76) | 1.32 (0.77–2.25) | 0.24 | |
HR, hazard ratio; MLE, major life event.
Adjusted for age and sex.
Adjusted for age, sex and vital exhaustion.
Adjusted for age, sex and traditional risk factors such as smoking, diabetes, physical activity, blood pressure and cholesterol lowering drugs, systolic blood pressure, body mass index, atrial fibrillation, blood lipids and familiar dispostion. Alcohol consumption, hormone replacement therapy and blood glucose were not associated with stroke or myocardial infarction in this study sample.
Adjusted for age, sex, vital exhaustion, traditional and socioeconomic risk factors such as cohabitation, education and household income. Employment was not associated with stroke or myocardial infarction in this study sample.
P value for test for trend.