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In the presence of hydrogen peroxide (H2O2), myeloperoxidase (MPO) biodegrades oxidized single-walled carbon nanotubes (o-SWCNTs) by two mechanisms: (1) reactive intermediates generated via the peroxidase cycle and (2) hypochlorite produced in the presence of chloride (Cl−). When antioxidants such as L-ascorbic acid (AA) and L-glutathione (GSH) are added to the system, the biodegradation of o-SWCNTs is mitigated.
