FIG 4 .

Effect of HIV-1 infection on cellular miRNA expression levels. This figure presents a comparison of the level of each cellular miRNA detected in uninfected and HIV-1-infected cells. Only miRNAs that represent ≥0.1% of the total miRNA pool were included. Panel A shows data obtained by comparison of RISC-associated small RNAs, while panels B, C, and D compare total miRNA levels. The lines delineate changes of 2-fold between samples. miRNAs that fall outside this 2-fold limit are indicated by name. Red dots represent miRNAs derived from the miR-17/92 cluster. For illustrative purposes, this figure assumes that cells each express 5 × 10⁴ miRNAs.