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. 2013 Feb 14;6(3):745–754. doi: 10.1242/dmm.011205

Fig. 3.

Fig. 3.

Immunohistochemistry for cleaved caspase-3 in a hearing-impaired animal. Brown staining marks cleaved caspase-3 activity. (A) Overview of the cochlea duct at the middle turn. The box marks the organ of Corti. (B) High magnification of the organ of Corti. Positive labeling for cleaved caspase-3 can be detected in Deiters’ cells, Hensen’s cells and Claudius’ cells. No staining can be detected in the inner and outer hair cells. (C) High magnification of the stria vascularis and the spiral ligament. No reaction can be detected. (D) Close-up of the spiral ganglion cells. No labeling can be visualized. OHC, outer hair cell; IHC, inner hair cell; CC, Claudius’ cells; DC, Deiters’ cells; HC, Hensen’s cells; SL, spiral ligament; SV, stria vascularis.