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Summary of the metal-chelate-Rev complexes.31, 32 M = Fe2+, Co2+, Ni2+, Cu2+. The sequence of the Rev peptide is shown above. The 7-coordinate geometries shown here for M-DOTA-Rev and M-DTPA-Rev are based on the X-ray crystal structures of [Fe-DOTA]1− and [Fe-DTPA]2−.33, 34