Figure 7. Main classes of molecules downregulated in Raldh2 ^−/− embryonic tissues, according to Ingenuity pathway analysis of the transcriptomic data.

Pie charts illustrate the distribution of gene products according to subcellular location (A) or protein function (B), when considering the overall set of affected genes (fold change ±1.2, filtered for FDR <10% and a p-value ≤0.03 for POST and ≤0.05 for ANT).