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. 2013 Apr 24;8(4):e62181. doi: 10.1371/journal.pone.0062181

Table 1. Characteristics of Eligible Studies.

First Author Year Country Histological types Source of controls Mean age of case/control Male (%) of case/control Smoke(%) ofcase/control NO. of cases NO. of controls
Lan 2000 China NA PB 55/55 64.8/64.8 100/100 122 122
London 2000 China NA PB NA/NA NA/NA NA/NA 232 710
Kiyohara 2000 Japan SqCC = 27.9%, SCLC = 14.0%, AC = 46.5%, LCC = 4.7%, others = 7.0% PB 63.8/59 100/100 45.5/68.6 86 88
Zhao 2001 Singapore NA HB 65.5/63.6 0/0 41.2/9.6 233 187
Sunaga 2002 Japan AC = 100% HB 63/65 62.6/71.7 60.6/63.8 198 152
Wang 2003 China AC = 100% PB 56.5/54.5 64.3/66.4 42.9/66.4 112 119
Liang 2004 China SqCC = 41.4%, AC = 58.6% HB 60.5/60.5 70.4/70.4 NA/NA 152 152
Sobti 2004 India SqCC = 71.0%, SCLC = 24.0%, AC = 4.0%, LCC = 1.0% PB 55.5/50.9 95/96.1 86.0/77.6 100 76
Chan 2004 China SqCC = 16.6%, AC = 55.5%, others = 27.9% PB 53.8/49.3 67.2/59.4 56.8/40.1 229 197
Yuan 2005 China SqCC = 46.7%, AC = 40.7%, others = 12.7% PB 57.1/54.7 76.7/77 65.3/34.2 150 152
Sreeja 2005 India NA PB 58.2/56.1 91.1/87.7 59.9/45.2 146 146
Chen 2006 China SqCC = 52.6%, AC = 44.3%, others = 3.1% PB 56.6/55.8 43.3/48.7 0/0 97 197
Lee 2006 Korea SqCC = 43.3%, SCLC = 18.1%, AC = 28.1%, others = 10.5% HB 61/62.1 100/100 91.7/81.4 171 196
Yang 2007 Korea SqCC = 22.3%, SCLC = 9.7%, AC = 54.7%, others = 13.3% PB 55.4/48.3 67.6/61.8 62.3/50.1 318 353
Sobti 2008 India SqCC = 63.5%, SCLC = 15.8%, AC = 7.2%, others = 7.9% HB 56.9/56.4 86/81.4 81.4/74.2 151 151
Sreeja 2008 India NSCLC = 81.0%, SCLC = 9.5%, others = 9.5% HB 57.8/56.2 86.3/87.2 68.2/56.4 211 211
Klinchid 2009 Thailand SqCC = 39.6% AC = 60.4% PB 59.8/57.8 64/46 80.0/34.0 91 82
Kumar 2009 India SqCC = 23.0%, SCLC = 14.0%, AC = 38.0%, LCC = 6.0%, others = 20.0% PB 42.6/39.8 87.1/80.2 81.0/100 93 253
Yadav 2010 India NA PB 58/58 76.2/68.3 80.0/47.0 101 221
Tamaki 2011 Japan SqCC = 24.5%, SCLC = 21.4%, AC = 41.7%, LCC = 0.5%, others = 11.9% HB 80.3/80.3 67.2/69 70.3/51.7 192 203
Fowke 2011 China NA PB NA/NA 0/0 NA/NA 209 787
Kiyohara 2012 Japan SqCC = 28.4%, SCLC = 14.9%, AC = 52.4%, LCC = 4.3% HB 66.1/55.9 62.1/74.7 66.9/44.8 462 379
Wang 2012 China SqCC = 49.3%, SCLC = 13.4%, AC = 33.0%, others = 4.3% PB 61.4/57.4 69.4/63.7 NA/NA 209 256

SqCC: squamous cell carcinoma; AC: adenocarcinoma; SCLC: small cell carcinoma; LCC: large cell carcinoma; NSCLC: non–small cell carcinoma; PB: population-based; HB: hospital-based.