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. 2013 Apr 24;8(4):e61773. doi: 10.1371/journal.pone.0061773

Figure 8. Abundant overlap of differentially regulated genes after puncture and trypsin puncture wounding.

Figure 8

At each of the three time points (30 minutes, 60 minutes, and 120 minutes) after puncture and trypsin puncture wounding, a comparison of the statistically significant (FDR <0.01) regulated genes was performed using Microsoft Excel software. (A) 30 minutes after puncture and trypsin puncture wounding, 15 and 112 significant genes respectively, were upregulated 1.8 fold or greater; 14 genes were commonly upregulated after both wounding treatments. 60 minutes post puncture and trypsin puncture wounding, 64 and 332 significant genes respectively, were upregulated 1.8 fold or greater; 58 genes were commonly upregulated after both wounding treatments. 120 minutes post puncture and trypsin puncture wounding, 210 and 624 significant genes respectively, were upregulated 1.8 fold or greater; 186 genes were commonly upregulated after both wounding treatments. (B) 30 minutes post puncture and trypsin puncture wounding, 389 and 378 significant genes respectively, were downregulated −1.8 fold or lower; 333 genes were commonly down regulated after both wounding treatments. 60 minutes post puncture and trypsin puncture wounding, 496 and 508 significant genes respectively, were downregulated −1.8 fold or lower; 429 genes were commonly downregulated after both wounding treatments. 120 minutes post puncture and trypsin puncture wounding, 698 and 826 significant genes respectively, were downregulated −1.8 fold or lower; 624 genes were commonly downregulated after both wounding treatments.