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. 2013 Apr 24;8(4):e61632. doi: 10.1371/journal.pone.0061632

Figure 1. Bone Marrow Soup re-established saliva secretion following irradiation.

Figure 1

A. At week 8 post-irradiation, BM Soup-treated mice (IR+BMSoup) had their salivary flow rate (SFR; ul/min/per g of body weight) restored to normal levels (100%; 0.4 ul/min) when compared to sham-irradiated mice (Control) and those transplanted with whole live BM cells (IR+BM). Mice receiving an intravenous injection of PBS (IR+PBS; vehicle control group) had 60% reduction in SFR (* P<0.05). B. Weights of the salivary glands relative to 100g of their body weights were higher in IR+BMSoup and IR+BM mice (* P<0.05). C. Saliva levels of epidermal growth factor (EGF) were not statistically different among the four groups of mice (P>0.05). N = 5 to 9 mice per group.