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. 2013 Apr 24;8(4):e61016. doi: 10.1371/journal.pone.0061016

Figure 7. Twenty-four hours of waking increases salivary ITGAM and ANXA3.

Figure 7

(A) Subjective sleepiness (SSS) is increased following 24 h of wakefulness. Each subject served as their untreated circadian-matched control; t-test p = 0.0003. (B) Lapses increased during waking compared to controls; t-test p = 0.028. (C) Mean reaction time, expressed as 1/RT, slowed; t-test p = 0.003 (D) Reaction times in the slowest 10% also slowed; t-test p = 0.016. (E) Salivary transcript levels for Integrin αM (ITGAM) and (F) Annexin (ANXA3) are increased following 24 hours of waking; t-test, p = 0.04 and p = 0.04, respectively; data are expressed as a percent change from control.