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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Pflugers Arch. 2012 Dec 15;465(6):805–818. doi: 10.1007/s00424-012-1193-9

Figure 1. Effect of β1-adrenergic and β2-adrenergic receptor blocker on isoproterenol-induced action potential duration shortening in control male and female rabbits.

Figure 1

A–B, Representative action potential recordings from female (A) and male (B) rabbit LV myocytes at a stimulation rate of 1 Hz at baseline, after the administration of 500nM isoproterenol (ISO) alone, or 500nM ISO plus 300nM β1-adrenergic receptor blocker CGP 20712A (ISO+CGP). C–D, Representative AP recordings from LV myocytes from female (C) and male (D) rabbits at baseline, after 500nM ISO, or 500nM ISO + 100nM ICI-118,551 (β2-adrenergic receptor blocker).