Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Time course of inhibition of APC derivatives by human plasma. APC derivatives (20 nM each) were incubated with normal plasma at 37 °C. At indicated time points, aliquots were removed, and the residual amidolytic activity was determined by the chromogenic substrate SpPCa as described in “Materials and methods”. The symbols are: APC wild-type (○), APC-R147W (●), and APC-K150del (□). Data are derived from at least three independent measurements (±SD).
