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a: control; b: HIF 5 µg/mL; c: doxorubicin 8 nmol; d: combination of doxorubicin 8 nmol and HIF 5 µg/mL; e: cell viability (%) of T47D cells using MTT method; f: cell viability profile of HIF on Vero cells. Data were expressed as (mean±SD). *Combination was considered significant comparing with doxorubicin single treatment (8 nmol) (P<0.01).
