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Pathways affected by miR-221, based on Genespring and GeneGo analysis of target genes.
| Pathway | Average p-valuesa | |
|---|---|---|
| GeneGo | Genespring | |
| Cell adhesion: ECM remodeling, Cadherin-mediated, Ephrin signaling | 8,55E-05 | 2,93E-03 |
| TGF, WNT, and cytoskeletal remodeling | 1,71E-05 | 2,89E-02 |
| P53 signaling pathway | 1,33E-04 | 2,20E-02 |
| Cell cycle regulation | 9,94E-05 | 2,16E-02 |
| Growth factors signaling | 7,10E-05 | 2,35E-02 |
| Signaling in macrophages, B and T lymphocytes | 1,78E-04 | 2,82E-02 |
Based on data of Table S6.
