Skip to main content
. Author manuscript; available in PMC: 2013 Apr 25.
Published in final edited form as: Front Biosci (Schol Ed). 2012 Jan 1;4:190–205. doi: 10.2741/s261

Figure 3.

Figure 3

Differential oncologic effects upon cells of the human brain with varying proliferative potential. Left: T1-weighted coronal MRI of the human brain. Top right: Drawing depicting the putative effect of chemical and mutational insults experimentally proposed to be involved in glioblastoma formation upon SVZ derived cells with proliferative capacity. Bottom right: Drawing depicting the absent or reduced effect upon subcortical/cortical cells known to have decreased proliferative capacity compared with the SVZ of chemical and insults experimentally proposed to be involved in glioblastoma formation. ENU - N-ethyl-N-nitrosourea; EGF - epithelial derived growth factor; PDGF - platelet derived growth factor, NF – neurofibromatosis.