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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Future Virol. 2013 Feb 1;8(2):129–157. doi: 10.2217/fvl.12.130

Table 3. Intravenous Macaca mulatta challenges with Congo Basin strain (Z79).

Dose Fever onset
(duration)		 Lesion onset
(maximum lesion
count)		 Mortality/euthanasia
(days of death)		 Blood vDNA
detected† (duration
of detection)		 Infectious virus
from swabs
(duration of
detection)		 Ref.
107 Day 2 (to day 8) 2/2 by day 13 Day 2 (to day 8) [111]
107 Day 6 (734) 0/0 (but severe disease) By day 3 (to day 15) [112]
107 Day 4 (TNTC) 3/3 (11, 17, 21) By day 3 (to day 9‡) [110]
107 Day 2–4 (to day 14) Day 6 (>100) 3/3 (7, 10, 14) Day 2–6 (to day 14) Throat from day 6
(to day 14)		 [51]
108 Only on day 2 in 1/2 No lesions 2/2 (6, 6) [51]
106 Day 2 (to day 8) Day 6 (>100) 0/2 (but severe disease) [51]
†

Does not include detection at day 0 following intravenous challenge.

‡

No samples taken from day 9.

TNTC: Too numerous to count; vDNA: Viral DNA.