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The substrate binding pocket of TbrPDEB1 (chain A) with the carbon atoms colored by B-factor, the range is shown on a color bar. Two water networks (red spheres) are shown with hydrogen bonds (gray dashes), one of which surrounds the invariant glutamine (Q874) and a second, which surrounds the metal ions. Pocket residues are shown as sticks and labeled where visible. The P-pocket is shown as a gray surface.
