Table 3. Cox proportional hazard models for overall survival.

	Univariable analysis				Multivariable analysis
	HR	95% CI	P-value		HR	95% CI	P-value
Age	1.03	1.01-1.05	<0.01		1.03	1.01-1.05	<0.01
T4 (vs. T3)	1.53	1.03-2.25	0.03		1.55	1.03-2.32	0.04
N1 (vs. N0)	1.07	0.65-1.52	0.53		-	-	-
Margin-negative resection	0.27	0.13-0.55	<0.01		0.30	0.14-0.63	<0.01
Treatment type (vs. C)
CRT	0.68	0.39-1.18	0.17		0.94	0.54-1.67	0.85
CCRT	0.55	0.34-0.89	0.02		0.58	0.35-0.95	0.03
CA 19-9	1.00	0.99-1.00	0.25		-	-	-

HR, Hazard Ratio; CI, Confidence Interval; C, Chemotherapy; CRT, Chemoradiation therapy; CCRT, Chemotherapy followed by chemoradiation therapy