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. 2013 Jun;4(2):144–157. doi: 10.3978/j.issn.2078-6891.2013.010

Table 3. Clinicopathological correlations of candidate genes expression in CRC.

Variable CXCL12 CXCR4 CXCR7 IL8 TGFB1 TGFBR1 TGFBR2 CDH17 CEA FABP1 MUC2 PDCD4
Tumour diameter 0.481 0.860 0.035* 0.285 0.766 0.189 0.155 0.043* 0.213 0.449 0.271 0.674
Tumour thickness 0.094 0.242 0.036* 0.616 0.348 0.317 0.234 0.035* 0.282 0.049 0.654 0.052
Wall involvement 0.019* 0.005* 0.002* 0.055 0.201 0.000* 0.006* 0.002* 0.002* 0.949 0.400 0.886
Tumour location 0.020* 0.381 0.021* 0.285 0.347 0.621 0.003* 0.473 0.858 0.466 0.711 0.007*
Tumour differentiation 0.043* 0.043* 0.596 0.008* 0.335* 0.443 0.560 0.045* 0.016* 0.109 0.910 0.209
Mucin secretion 0.342 0.272 0.679 0.115 0.585 0.225 0.870 0.407 0.782 0.398 0.013* 0.217
Depth of invasion 0.001* 0.093 0.485 0.319 0.828 0.217 0.116 0.587 0.442 0.389 0.645 0.487
Lymph node status 0.040* 0.059 0.287 0.015* 0.238 0.688 0.049* 0.175 0.071 0.976 0.716 0.934
Distant metastasis 0.163 0.044* 0.138 0.062 0.861 0.161 0.235 0.434 0.547 0.373 0.938 0.443
Perineural invasion 0.389 0.126 0.904 0.670 0.792 985 0.030* 0.180 0.154 0.057 0.443 0.969
LV invasion 0.033* 0.132 0.020* 0.0687 0.035 0.208 0.012* 0.016* 0.019* 0.515 0.131 0.600
Tumour stage 0.016* 0.253 0.749 0.676 0.490 0.534 0.370 0.949 0.681 0.704 0.911 0.649
Recurrence 0.169 0.058 0.124 0.036* 0.476 0.126 0.213 0.891 0.801 0.170 0.685 0.023*

*Statistically significant (P<0.05)