Table 5. OTUs enriched in specific treatments, the nearest related isolate genome and number of VFs.

Treatment Enriched	OTU	Phylum/class	Best genomic match	% ID	# VFs
Amansia	OTU854	Flavobacteria	Fluviicola taffensis DSM 16823	88	541
Amn/Hala	OTU14	α-Proteobacteria	Ruegeria spp. TM1040	91	672
Halimeda	OTU162	Flavobacteria	Fluviicola taffensis DSM 16823	84	541
Porites	OTU173	α-Proteobacteria	No genome >80% identity	NA	NA
Porites	OTU136	γ-Proteobacteria	Cellvibrio japonicus Ueda107	91	750
Porites	OTU50	α-Proteobacteria	Hyphomonas neptunium	92	559
Porites	OTU642	γ-Proteobacteria	Congregibacter litoralis KT71	92	652
Porites	OTU115	α-Proteobacteria	Micavibrio aeruginosavorus	85	390
Porites	OTU197	α-Proteobacteria	Erythrobacter litoralis	99	430
Turbinaria	OTU6	γ-Proteobacteria	Pseudoalteromonas spp. SM9913	91	727
Turbinaria	OTU27	γ-Proteobacteria	Pseudoalteromonas spp. SM9913	92	727
Turbinaria	OTU39	γ-Proteobacteria	Alteromonas spp. SN2	93	789
Turbinaria	OTU18	γ-Proteobacteria	Alteromonas macleodii	93	759
Turbinaria	OTU59	γ-Proteobacteria	Vibrio splendidus LGP32	93	875
Turbinaria	OTU102	γ-Proteobacteria	Vibrio splendidus LGP32	93	875
Turbinaria	OTU174	α-Proteobacteria	Ruegeria pomeroyi DSS-3	87	690
Turbinaria	OTU100	α-Proteobacteria	Ruegeria spp. TM1040	93	672
Turbinaria	OTU17	γ-Proteobacteria	Pseudoalteromonas spp. SM9913	95	727
Ambient	OTU43	α-Proteobacteria	Pelagibacter ubique HTCC1062	89	240
Ambient	OTU9	α-Proteobacteria	Pelagibacter ubique HTCC1062	97	240
Ambient	OTU38	Flavobacteria	Fluviicola taffensis DSM 16823	87	541
Ambient	OTU22	Cyanobacteria	Synechococcus spp. CC9605	96	289
Ambient	OTU15	α-Proteobacteria	No genome >80% identity	NA	NA

Abbreviations: ID, identity; NA, not applicable; OTU, operational taxonomic unit; VF, virulence factor.

^aOTU14 was enriched in both Amansia and Halimeda treatments. Queries all >250 bp and expect scores all <e⁻05.