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. Author manuscript; available in PMC: 2013 Oct 12.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Sep 16;427(1):165–170. doi: 10.1016/j.bbrc.2012.09.035

Figure 3. TGF β1 increased phosphorylation of p38 MAPK and SAPK/JNK and enhanced expression of cleaved caspases in PC3 and T24 cells.

Figure 3

(A) Western blots showing increased phosphorylation of p38-MAPK and SAPK/JNK, as well as increased expression of cleaved caspase-9, cleaved caspase-8, and cleaved caspase-3 after 24 h treatment with TGFβ1 (0.1, 0.5, 1, 2.5, and 5 ng/ml) compared to control (DMEM) (B–F) Bar graphs showing band-densitometry analysis of phoshorylations of p38 MAPK, SAPK and expression of cleaved caspase-9, cleaved caspase-8 and cleaved caspase-3, respectively, with TGFβ1 treatment as mentioned above, normalized to β-actin.