Table 2.
Original 7PCL with performance for each cut-point in detecting clinically significant lesions and melanoma. (Score of ≥3 used as cut-point in Original 7PCL)
| Score | Clinically significant | Melanoma | ||||
|---|---|---|---|---|---|---|
| Sensitivity | Specificity | Test of associationa | Sensitivity | Specificity | Test of associationb | |
| ≥1 | 95.1% (214/225) | 7.5% (91/1211) | 0.160 | 100% (36/36) | 7.3% (102/1400) | 0.110 |
| ≥2 | 81.8% (184/225) | 31.3% (379/1211) | <0.001 | 94.4% (34/36) | 29.9% (418/1400) | <0.001 |
| ≥3 | 62.7% (141/225) | 65.0% (787/1211) | <0.001 | 80.6% (29/36) | 61.7% (864/1400) | <0.001 |
| ≥4 | 36.4% (82/225) | 86.5% (1048/1211) | <0.001 | 55.6% (20/36) | 83.9% (1175/1400) | <0.001 |
| ≥5 | 14.2% (32/225) | 96.6% (1170/1211) | <0.001 | 25.0% (9/36) | 95.4% (1336/1400) | <0.001 |
| ≥6 | 4.9% (11/225) | 99.3% (1203/1211) | <0.001 | 5.6% (2/36) | 98.8% (1383/1400) | 0.080 |
a
P-values are from the χ2 test of association between item and reference standard.
b
P-values are from Fisher’s exact test of association between item and reference standard