Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Quality of life
Systematic review	101 people, approximately 80% men, mean age range 43 to 47 years 2 RCTs in this analysis	Global quality-of-life score (EORTC questionnaire) with pancreaticoduodenectomy with duodenum-preserving pancreatic head resection Absolute numbers not reported	WMD 25.07 95% CI 18.93 to 31.31 P <0.0001	Effect size not calculated	duodenum-preserving pancreatic head resection
RCT	46 people Further report of reference	Global quality-of-life score (EORTC questionnaire) 7 years with pylorus-preserving pancreaticoduodenectomy with limited pancreatic head excision with extended drainage (Frey procedure) Absolute numbers not reported	P = 0.974		Not significant