Table 6.
Bioavailability (and 90% CIs) of the non-fasting regimen of ABT-288 relative to the fasting regimen (5 mg single dose)
| Parameter | Central value* | Relative bioavailability | ||
|---|---|---|---|---|
| Point estimate† | 90% CIs | |||
| Non-fasting | Fasting | |||
| Cmax (ng ml−1) | 2.87 | 2.92 | 0.985 | 0.871, 1.114 |
| AUC(0,tlast) (ng h ml−1) | 105 | 100 | 1.042 | 0.995, 1.091 |
| AUC(0,∞) (ng h ml−1) | 127 | 124 | 1.022 | 0.960, 1.088 |
Antilogarithm of the least squares means for logarithms.
Antilogarithm of the difference (test − reference) of the least squares means for logarithms.