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The histologic section showed brain parenchyma infiltrated by numerous small-to-medium sized neoplastic cells with perivascular cuffing of neoplastic cells (A, HE ×100) and the neoplastic cells had irregular nuclei with a moderate amount of cytoplasm (B, HE ×400). Large atypical cells with horseshoe shaped nuclei, which are hallmark cells of anaplastic large cell lymphoma, were also present (B, inset, HE ×1000)
