Figure 4.
Improving intravenous delivery of acidic fibroblast growth factor to the ischemic myocardium by heparin-modified microbubbles (aFGF-HMB) combined with the UTMD technique. (A) Illustration of the method of administration. (B) M-mode echocardiography for the group that received aFGF-HMB combined with US (ultrasound).29
Note: Copyright © 2012. Informa Healthcare. Reproduced with permission from Zhao Y, Lu C, Li X, et al. Improving the cardio protective effect of aFGF in ischemic myocardium with ultrasound-mediated cavitation of heparin modified microbubbles: preliminary experiment. J Drug Target. 2012;20:623–631.29
Abbreviations: IVST, intraventricular septum thickness; LVDd, left ventricular diastolic dimension; LVPW, left ventricular posterior wall; UTMD, ultrasound-targeted microbubble destruction.