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. Author manuscript; available in PMC: 2013 Apr 25.
Published in final edited form as: J Immunol. 2011 Jun 20;187(2):911–918. doi: 10.4049/jimmunol.1100588

Figure 1. Polymicrobial sepsis induces bone marrow neutrophil efflux into the circulation.

Figure 1

Panel A and B. Percentage and cell number of GR-1+CD11b+ neutrophil fluctuations in the bone marrow and blood 96 hours after polymicrobial sepsis. Panels C and D. Percentage of total GR-1+CD11b+ neutrophils in the blood and bone marrow 12 hours after sham or cecal ligation and puncture procedure (CLP). Panel E. Percentage of the total GR-1+CD11b+ population that is F4/80+ in the blood after either sham or CLP induced sepsis. Panel F. Percentage of the total GR-1+CD11b+ population that stain positive for CD31 in the blood after either sham or CLP induced sepsis. Values for panels A-E represent the mean and standard error of 5 animals per group from three independent experiments. B and C * p<0.01 by analysis of variance between Cont (healthy animal), Sham, and CLP treated mice. D and E # p<0.01, by Student’s t-test between Sham and CLP.