Skip to main content
. Author manuscript; available in PMC: 2013 Apr 25.
Published in final edited form as: J Immunol. 2011 Jun 20;187(2):911–918. doi: 10.4049/jimmunol.1100588

Figure 7. CXCL12 blockade reduces survival to polymicrobial sepsis.

Figure 7

Anti-CXCL12 or anti-CXCR2 were administered 12 hours before the onset of sepsis and once daily for the next 7 days. CXCL12 blockade produced a significant reduction (40%) in survival following the initiation of polymicrobial sepsis. The survival analysis was repeated two times with n=20 mice/group in each experiment. Statistical analysis was done using a Fisher’s Exact test of significance p=0.025.