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Validation of the “small effect” assumption for FWHM estimation. Histograms of the FWHM in voxels estimated in three directions, for 1000 randomly selected SNPs (blue) and the FWHM from the no-SNP model marked in red. The FWHM from the no-SNP model appears to be an excellent surrogate for individual SNP models, rarely differing by more than 0.005 in any direction.
