Skip to main content
. 2013 Apr 1;123(5):2064–2077. doi: 10.1172/JCI64375

Figure 3. MKP-5 deficiency in mdx mice leads to ameliorated myopathy.

Figure 3

(A) H&E staining of the diaphragm (Dia.) and gastrocnemius (Gas.) muscles. Scale bar: 50 μm. (B) Evans blue dye uptake. Scale bar: 100 μm. (C) Masson’s trichrome staining. Scale bar: 300 μm. (D) Degenerating area percentage (>10 degenerating myofibers) of total gastrocnemius muscle sections. (E) Evans blue dye area percentage of the gastrocnemius section. (A–E) n = 6 per genotype; mice were 3-month-old males. (F) Serum creatine kinase (CK) activity (n = 6 per genotype; 4-month-old male mice). Results are the mean ± SEM. **P < 0.01 compared with mdx/Mkp5+/+ mice.