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Example from the SCOPE 1 (Study of Chemoradiotherapy in Oesophageal Cancer Plus or Minus Erbitux) trial. (A) shows the original reference gross tumour volume (GTV) (yellow), defined by the chief investigator and an upper GI radiologist and the GTVs delineated by the other 3 clinical oncology members of the SCOPE 1 trial management group. (B) shows the STAPLE derived consensus GTV (red) with the original reference GTV in yellow.
