. Author manuscript; available in PMC: 2013 Apr 25.

Published in final edited form as: Surgery. 2011 Dec;150(6):1186–1193. doi: 10.1016/j.surg.2011.09.026

Table I.

Summary clinical data of SDHB+ versus sporadic patients presenting with paraganglioma

	SDHB+	Sporadic
Mean age at diagnosis, yrs	28	39^*
Mean time to diagnosis, yrs	3.6 ± 4.2	4.6 ± 5.2
Acute presentation	7.1%	18.8% (P = .14)
Incidental detection	5.4%	6.3%
Metastatic/multifocal at presentation	38.5%	16.7%^*
Overall rate of metastatic disease	78.9%	48.3%^*
Local recurrence after resection	12.3%	20%
Secondary PGL	7.0%	6.7%

Indicates statistically significant difference between groups (P < .05). Overall, SDHB+ patients presented at a younger age and were more likely to present with and develop metastatic or multifocal disease.

PGL, Paraganglioma; SDHB+, succinate dehydrogenase positive.