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Percentage of H-460 cells in late or early apoptosis at the end of treatment period either with doxorubicin or P276-00 alone or in the combination of doxorubicin followed by P276-00
|
Treatment group |
Percentage of cells |
|||
|---|---|---|---|---|
| Live cells | Annexin +ve | Annexin + PI | PI +ve | |
| Control |
90.5 |
3 |
4 |
2.3 |
| Doxorubicin ( 100 nM) |
60 |
30.4 |
8.6 |
1 |
| P276-00 (1200 nM) |
53 |
38.5 |
8.2 |
0.3 |
| Doxorubicin> P276-00 | 14.1 | 50.2 | 34.3 | 2 |
