Table 2.
Levels of serum miRNAs (mean ± SD), PG (median ± SD) between different gastric disease groups
| Variables | CON | AG | GC | P-value | |
|---|---|---|---|---|---|
| miR-20a-5p |
|
3.77 ± 0.74 |
3.84 ± 0.69 |
3.83 ± 0.68 |
0.581 |
| |
Male |
3.80 ± 0.77 |
3.90 ± 0.73 |
3.88 ± 0.78 |
0.59 |
| |
Female |
3.72 ± 0.69 |
3.73 ± 0.60 |
3.75 ± 0.47 |
0.855 |
| let-7a |
|
3.72 ± 0.34 |
3.77 ± 0.29 |
3.75 ± 0.28 |
0.445 |
| |
Male |
3.72 ± 0.31 |
3.78 ± 0.32 |
3.77 ± 0.28 |
0.367 |
| |
Female |
3.71 ± 0.39 |
3.76 ± 0.24 |
3.72 ± 0.28 |
0.93 |
| miR-320a |
|
4.99 ± 0.46 |
4.94 ± 0.45 |
4.90 ± 0.44 |
0.152 |
| |
Male |
5.03 ± 0.49 |
5.01 ± 0.46 |
5.00 ± 0.42 |
0.76 |
| |
Female |
4.93 ± 0.40 |
4.81 ± 0.39 |
4.73 ± 0.43 |
0.035* |
| PGA |
|
146.3 ± 101.5 |
111.0 ± 85.4 |
130.1 ± 107.1 |
0.044§ |
| PGC |
|
19.2 ± 17.6 |
14.0 ± 12.2 |
23.1 ± 23.0 |
0.003§ |
| PGA/PGC | 9.52 ± 4.85 | 9.52 ± 5.23 | 7.86 ± 5.46 | 0.039§ |
P*:GC vs Control; P§:difference among the three groups. CON: Cases with minimal superficial gastritis were treated as the controls; AG: atrophic gastritis; GC: gastric cancer.