Table 3.
Prediction of abnormal 6-hour aEEG with different encephalopathy assessment methods at 3 – 5 hours
| Encephalopathy assessment | n | Abnormal aEEG n (%) | Sensitivity (95%CI) | Specificity (95%CI) | LR + (95%CI) | LR - (95%CI) | LR Test (Odds ratio) (95%CI) | |
|---|---|---|---|---|---|---|---|---|
| Moderate-severe encephalopathy |
Yes |
42 |
35 (83) |
97% |
71% |
3.2 a |
0.06 a |
55.22 a |
| No |
18 |
1 (6) |
(86 – 100) |
(49 – 87) |
(1.75 – 5.84) |
(0.01 – 0.28) |
(8.73 – 349.15) |
|
| Thompson score ≥ 7 |
Yes |
44 |
36 (82) |
100% |
67% |
2.9 a |
0.02 a |
141.71 a |
| No | 16 | 0 (0) | (90 – 100) | (45 – 84) | (1.7 – 5) | (0 – 0.33) | (7.71 – 2603.42) | |
LR: Likelihood ratio, aEEG: amplitude-integrated EEG,
a : When zero count cells are present, LR is estimated using a substitution formula: 0.5 is added to all cell frequencies before calculation.