Table 6.
Short-term neurological outcomes
| Outcome | Whole cohort n = 60 (100%) | Thompson < 7 n = 16 (100%) | Thompson ≥ 7 n = 44 (100%) |
|---|---|---|---|
| Mild encephalopathy a |
12 (20) |
11 (69) |
1 (2) * |
| Moderate encephalopathy a |
27 (45) |
5 (31) |
22 (50) * |
| Severe encephalopathy a |
21 (35) |
0 |
21 (48) * |
| aEEG or Clinical Seizure |
35 (58) |
0 |
35 (80) * |
| Mean core temperature age 3 hours (±SD) |
35.3 (±1.1) |
36.3 (±0.4) |
34.9 (±1.0) * |
| aEEG normal at 6 and 24 hours |
23 (38) |
16 (100) |
7 (16) * |
| aEEG abnormal age 3 hours (n=50) |
33 (66) |
2(13) |
31(71) * |
| aEEG abnormal age 6 hours |
36 (60) |
0 |
36 (82) * |
| aEEG abnormal age 3 or 6 hours |
40 (67) |
2(13) |
38 (86) * |
| aEEG severely abnormal age 6 hours |
25 (42) |
0 |
25 (57) * |
| aEEG severely abnormal age 24 hours |
18 (30) |
0 |
18 (41) ** |
| Dead or aEEG severely abnormal age 48 hours |
12 (20) |
0 |
12 (27) † |
| Maximum Thompson score ≥ 15 |
21 (35) |
0 |
21 (48) ** |
| Dead or maximum Thompson Score ≥ 15 |
22 (37) |
0 |
22 (50) * |
| Dead |
8 (13) |
0 |
8 (19) ‡ |
| Median age at death, d (Range) (n=8) |
2 (1.5 – 5) |
- |
2 (1.5 – 5) |
| Thompson score normal (0) by day 7 | 22 (42) | 13 (81) | 9 (25) * |
LOC: Level of consciousness, aEEG: amplitude-integrated EEG.
a: Highest modified Sarnat encephalopathy grade recorded in the first 72 hours.
* p<0.0001, ** p=0.001, † p=0.025, ‡ p=0.09.