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. 2013 Apr 25;9(4):e1003474. doi: 10.1371/journal.pgen.1003474

Figure 4. T-STAR protein regulates region-specific splicing of Neurexin1-3 AS4 in the mouse brain.

Figure 4

(A) Neurexin splicing regulation in different regions of the mouse brain (B) Schematic of the different mouse brain regions used for analysis. (C–E) Percentage splicing exclusion in different regions of the mouse brain (n = 3 mice from each genotype) measured in RNA samples from wild type (column +) and knockout (column −) mice for AS4 of (C) Nrxn1, (D) Nrxn2 and (E) Nrxn3. The error bars correspond to the standard error of the mean. Statistical significances were calculated using a two tailed unpaired t test. No splicing exclusion was observed for Nrxn3 in the absence of T-STAR protein in any brain region.