. Author manuscript; available in PMC: 2014 May 1.

Published in final edited form as: Int J Gynecol Cancer. 2013 May;23(4):716–723. doi: 10.1097/IGC.0b013e318286a95d

Table 3.

Cumulative incidence and risk of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) in association with varied HPV viral load among normal women or women with CIN1 at baseline, stratified by combinations of HPV viral load at baseline and follow-up.

HPV Viral Load	No. CIN2+/No. women	Cumulative Incidence of CIN2+	aHR^‡	95% CI
Repeat Negative	2/1199	0.2%	1	-
Single/ Repeat Low load^†	0/124	-	-	-
Single Moderate/ High load at baseline	3/100	3.0%	19.1	3.2–114.5
Single Moderate/ High load at follow up	1/97	1.0%	6.8	0.6–74.8
Repeat Moderate/ High load^†	11/38	29.0%	188.8	41.2–864.1

^†

Viral load categories represent the maximum measured viral load for a given woman for either time point.

^‡

aHR=Hazard Ratio adjusted for age, number of full-term births and number of lifetime sexual partners.