Table 1.
Characteristics of Older Patients with Major Depression with High (AES1≥36.5) and Low (AES<36.5) Apathy Scores and Normal Elders.
| Variable | Apathetic Depressed (N=7) | Non-Apathetic Depressed (N=9) | Normal Elders (N=10) |
|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | |
| Age | 69.9 (4.9) | 68.3 (6.1) | 68.6 (7.0) |
| Education | 17.0 (2.8) | 17.3 (2.1) | 16.3 (3.8) |
| AES1-Patient Self-Rated | 43.6 (5.3)* | 30.1 (4.2) | 22.5 (2.7)** |
| MADRS2 | 25.6 (4.4) | 21.9 (3.0) | 2.1 (1.3)*** |
| MiniMental State Exam | 28.9 (1.1) | 29.3 (0.7) | 28.5 (0.97) |
| DRS3 Total | 134.9 (5.3) | 137.8 (3.3) | 137.3 (3.9) |
| DRS Initiation/Perseveration | 33.9 (4.4) | 36.0 (0.7) | 35.9 (1.1) |
| Stroop Color Word | 33.9 (11.5) | 36.4 (8.3) | 38.5 (6.8) |
| Trails A | 38.3 (7.7) | 33.5 (9.9) | 30.0 (11.1) |
| Trails B | 96.8(44.1) | 81.2 (18.2) | 75.7 (25.3) |
| HVLT-R4 Immediate Recall | 25.4 (5.2) | 28.2 (4.0) | 25.5 (5.1) |
| HVLT-R Delayed Recall | 9.1 (2.2) | 9.1 (2.2) | 9.5(2.2) |
1
Apathy Evaluation Scale;
2
Montgomery Asberg Depression Rating Scale;
3
Dementia Rating Scale;
4
Hopkins Verbal Learning Test-Revised;
Mann-Whitney comparisons:
*
Apathetic Depressed vs. Non-Apathetic Depressed p<0.001,
**
Normal Elders vs. Non-Apathetic Depressed p = 0.002,
***
Normal elders vs. Apathetic Depressed p = 0.001, Normal Elders vs. Non-Apathetic Depressed p < 0.001.