Table 2. Basic characteristics for women exposed to an antidepressant during pregnancy.
| SSRI | TCA | Others | Any AD | No exposure | ||
| (N = 16 928) | (N = 1297) | (N = 3135) | (N = 19740) | (N = 892582) | ||
| Characteristic | n (%) | n (%) | n (%) | n (%) | n (%) | p-value |
| Education | <0.001 | |||||
| Unskilled | 7645 (45.16) | 557 (42.95) | 1572 (50.14) | 8991 (45.55) | 291155 (32.62) | |
| Skilled | 4524 (26.72) | 393 (30.30) | 818 (26.09) | 5287 (26.78) | 265794 (29.78) | |
| Higher | 4345 (25.67) | 312 (24.06) | 647 (20.64) | 4950 (25.08) | 295149 (33.07) | |
| Missing values | 414 (2.45) | 35 (2.70) | 98 (3.13) | 512 (2.59) | 40484 (4.54) | |
| Annual household income | <0.001 | |||||
| Less than $ 62 192 | 6174 (36.47) | 402 (30.99) | 1315 (41.95) | 7248 (36.72) | 216452 (24.25) | |
| $ 62 192–$ 89 140 | 4313 (25.48) | 405 (31.23) | 836 (26.67) | 5081 (25.74) | 218620 (24.49) | |
| $ 89 141–$ 126 344 | 3290 (19.44) | 244 (18.81) | 510 (16.27) | 3768 (19.09) | 219935 (24.64) | |
| $ 126 345 or greater | 2816 (16.64) | 225 (17.35) | 391 (12.47) | 3215 (16.29) | 220490 (24.70) | |
| Missing values | 335 (1.98) | 21 (1.62) | 92 (2.93) | 428 (2.17) | 1785 (0.20) | |
| Age (years) | <0.001 | |||||
| <20 | 530 (3.13) | 15 (1.16) | 97 (3.09) | 599 (3.03) | 24447 (2.74) | |
| 21–25 | 2748 (16.23) | 163 (12.57) | 538 (17.16) | 3185 (16.13) | 135330 (15.16) | |
| 26–30 | 5486 (32.41) | 374 (28.84) | 995 (31.74) | 6338 (32.11) | 335476 (37.58) | |
| 31–35 | 5396 (31.88) | 441 (34.00) | 963 (30.72) | 6308 (31.96) | 286027 (32.04) | |
| >35 | 2768 (16.35) | 304 (23.44) | 542 (17.29) | 3310 (16.77) | 111302 (12.47) | |
| Missing values | 0 (−) | 0 (−) | 0 (−) | 0 (−) | 0 (−) | |
| Parity | <0.001 | |||||
| 1 | 7430 (43.89) | 497 (38.32) | 1397 (44.56) | 8646 (43.8) | 389794 (43.67) | |
| 2 | 5483 (32.39) | 386 (29.76) | 860 (27.43) | 6255 (31.69) | 327381 (36.68) | |
| >2 | 3858 (22.79) | 402 (30.99) | 849 (27.08) | 4658 (23.6) | 169875 (19.03) | |
| Missing values | 157 (0.93) | 12 (0.93) | 29 (0.93) | 181 (0.92) | 5532 (0.62) | |
| Daily cigarettes | <0.001 | |||||
| 0 | 11147 (65.85) | 859 (66.23) | 1869 (59.62) | 12890 (65.3) | 705637 (79.06) | |
| 1–10 | 4245 (25.08) | 315 (24.29) | 937 (29.89) | 5043 (25.55) | 130280 (14.60) | |
| 11–20 | 294 (1.74) | 19 (1.46) | 71 (2.26) | 350 (1.77) | 5240 (0.59) | |
| >20 | 680 (4.02) | 47 (3.62) | 138 (4.40) | 793 (4.02) | 22269 (2.49) | |
| Missing values | 562 (3.33) | 57 (4.39) | 120 (3.83) | 664 (3.37) | 29156 (3.27) | |
| BMI (kg/m2) | <0.001 | |||||
| <18.5 | 811 (4.79) | 34 (2.62) | 154 (4.91) | 932 (4.72) | 27743 (3.11) | |
| 18.5–24.9 | 6279 (37.09) | 361 (27.83) | 1156 (36.87) | 7202 (36.48) | 247064 (27.68) | |
| 25.0–29.9 | 2678 (15.82) | 187 (14.42) | 574 (18.31) | 3123 (15.82) | 85611 (9.59) | |
| 30 | 2078 (12.28) | 153 (11.80) | 435 (13.88) | 2414 (12.23) | 47632 (5.34) | |
| Missing values | 5082 (30.02) | 562 (43.33) | 816 (26.03) | 6069 (30.74) | 484532 (54.28) |
Table shows the number (n) of pregnant women within each subcategory. Some women were exposed to several antidepressants during pregnancy. Number in parenthesis denotes percentage of pregnant women within each exposure. Information on BMI was only available for women giving birth after 1 January 2004. Chi-square tests were used to assess the overall p value for the group comparison between unexposed and women exposed to “any AD”.BMI, body mass index; SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressants; AD, antidepressant.