Table 2. Sociodemographic and molecular epidemiological associations of community-associated MRSA (CA-MRSA) and healthcare-associated MRSA (HCA-MRSA) in New Zealand, 2005–2011.
| Category | Subcategory | CA-MRSA (n = 1346) | HCA CO-MRSA (n = 1132) | HCA-HO-MRSA (n = 400) | CA-MRSA vs. HCA CO-MRSA | CA-MRSA vs. HCA HO-MRSA | ||
| P | OR (95% CI) | P | OR (95% CI) | |||||
| Age, median, years (IQR) | 27 (10–47) | 50 (19–78) | 64 (29–80) | <0.001a | – | <0.001a | – | |
| Gender | Male | 692 (51.4) | 590 (52.1) | 230 (57.5) | 0.75 | 0.97 (0.83–1.14) | 0.032 | 0.78 (0.62–0.99) |
| Female | 654 (49.6) | 542 (47.9) | 170 (42.5) | – | – | – | – | |
| Ethnicity | European | 470 (34.9) | 559 (49.4) | 230 (57.5) | 0.001 | 0.8 (0.6–0.9) | <0.001 | 0.4 (0.3–0.5) |
| Maori | 466 (34.7) | 332 (29.3) | 97 (24.2) | 0.005 | 1.3 (1.1–1.5) | <0.001 | 1.7 (1.3–2.2) | |
| Pacific Peoples | 345 (25.6) | 203 (17.9) | 58 (14.5) | <0.001 | 1.6 (1.3–1.9) | <0.001 | 2.1 (1.5–2.8) | |
| Other | 65 (4.8) | 38 (3.4) | 15 (3.8) | 0.07 | 1.5 (0.9–2.2) | 0.36 | 1.3 (0.7–2.4) | |
| NZDep score | 1–3 (low deprivation) | 158 (11.7) | 171 (15.1) | 70 (17.5) | 0.014 | 0.7 (0.6–0.9) | 0.003 | 0.6 (0.5–0.9) |
| 4–7 (medium deprivation) | 362 (26.9) | 311 (27.5) | 129 (32.2) | 0.75 | 0.9 (0.8–1.2) | 0.036 | 0.8 (0.6–1.0) | |
| 8–10 (high deprivation) | 826 (61.4) | 650 (57.4) | 201 (50.3) | 0.046 | 1.2 (1.0–1.4) | <0.001 | 1.6 (1.2–2.0) | |
| MRSA clone | ST30-IV | 438 (32.5) | 232 (20.5) | 50 (12.5) | <0.001 | 2.2 (1.8–2.7) | <0.001 | 3.4 (2.4–4.7) |
| ST5-IV | 335 (24.9) | 218 (19.3) | 48 (12.0) | 0.001 | 1.4 (1.1–1.7) | <0.001 | 2.4 (1.7–3.4) | |
| ST22-IV | 87 (6.5) | 282 (24.9) | 154 (38.5) | <0.001 | 0.25 (0.2–0.3) | <0.001 | 0.1 (0.001–0.2) | |
| ST1-IV | 161 (11.9) | 106 (9.4) | 38 (9.5) | 0.04 | 1.3 91.0–1.7) | 0.17 | 1.3 (0.9–1.9) | |
| ST8-IV | 80 (5.9) | 66 (5.8) | 23 (5.8) | 0.93 | 1.0 (0.7–1.5) | 1.0 | 1.0 (0.6–1.7) | |
| ST93-IV | 64 (4.8) | 33 (2.9) | 9 (2.2) | 0.02 | 1.7 (1.1–2.7) | 0.03 | 2.2 (1.6–4.7) | |
| ST239-III | 5 (0.4) | 22 (1.9) | 29 (7.3) | <0.001 | 0.2 (0.1–0.5) | <0.001 | 0.05 (0.02–0.1) | |
Note: Data are number (%) of patients unless stated otherwise.
a
Mann-Whitney U test.
Abbreviations: OR, odds ratio; CI, confidence interval; IQR, interquartile range; ST, sequence type, NZDep, New Zealand Deprivation Index score; MRSA, methicillin-resistant Staphylococcus aureus.