Table 1. Clinical and demographic characteristics of the study population.
CD n = 805 | UC n = 816 | ||||
Gender | |||||
F | 321 | 40% | 344 | 42% | |
M | 484 | 60% | 472 | 58% | |
Duration of follow-up (yr) | |||||
mean ± SD | 8±7 | 9±7 | |||
median ± SD | 6 (1–37) | 7 (1–41) | |||
Age at diagnosis (yr) | |||||
mean ± SD | 30±14 | 32±16 | |||
median ± SD | 28 (1–80) | 30 (1–75) | |||
Early onset (<19 yrs) | 155 | 20% | 148 | 19% | |
Adult (≥19 yrs) | 622 | 80% | 640 | 81% | |
Missing | 28 | 28 | |||
≤16 (A1) | 130 | 17% | 125 | 16% | |
17–40 (A2) | 483 | 62% | 456 | 58% | |
>40 (A3) | 164 | 21% | 207 | 26% | |
Missing | 28 | 28 | |||
Disease localization CD, n | |||||
Ileum (L1± L4) | 256 | 36% | |||
Colon (L2± L4) | 171 | 24% | |||
Ileo-colon (L3± L4) | 286 | 40% | |||
Upper GI (L4) | 6 | 1% | |||
Missing | 86 | ||||
Disease extent UC, n | |||||
Rectum (E1) | 95 | 12% | |||
Left colon (E2) | 374 | 47% | |||
Pancolitis (E3) | 322 | 41% | |||
Missing | 25 | ||||
Disease behavior CD, n | |||||
Inflammatory | 475 | 61% | |||
Stricturing | 209 | 27% | |||
Penetrating | 94 | 12% | |||
Missing | 27 | ||||
Perianal desease y/n | 143/630 | 18% | 20/765 | 3% | |
Missing | 32 | 31 | |||
Extra-intestinal manifestations y/n | 327/446 | 42% | 194/554 | 26% | |
Missing | 32 | 68 | |||
Family history of IBD y/n | 55/725 | 7% | 64/729 | 8% | |
Missing | 25 | 23 | |||
Smoking history | |||||
Yes | 229 | 30% | 110 | 14% | |
No | 402 | 53% | 444 | 57% | |
Ex | 127 | 17% | 222 | 29% | |
Missing | 47 | 40 | |||
Surgery y/n | 258/527 | 33% | 77/711 | 10% | |
Missing | 20 | 28 | |||
Steroids y/n | 510/295 | 63% | 514/302 | 63% | |
*Refractory | 73 | 14% | 71 | 14% | |
*Responder+dependent | 433 | 86% | 438 | 86% | |
IMS (AZT/6MP, CICLO, MTX) | |||||
Yes | 302 | 38% | 217 | 27% | |
No | 503 | 62% | 599 | 73% | |
Non Responder | 17 | 15% | 3 | 23% | |
Responder | 96 | 85% | 10 | 77% |
Steroids_Resp-DepvsRefrac.
CD: Crohn's disease, UC: ulcerative colitis, IMS: immunosuppressors.