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. 2012 May 4;35(3):763–776. doi: 10.1007/s11357-012-9410-1

Table 1.

Protein-coding genes significantly differentially expressed at 6- to 12-, 6- to 28-, and 12- to 28-month-old rats

Ensembl ID Gene symbol Gene name Log2 fold change FDR
6- vs. 12-month-old rats
ENSRNOG00000008080 Hrh3 Histamine H3 receptor −2.02 0.002
6- vs. 28-month-old rats
ENSRNOG00000019342 Sult1a1 Sulfotransferase 1A1 1.74 3.16 × 10−07
ENSRNOG00000033526 Hspa1a Heat shock 70 kDa protein 1A/1B −2.11 0.021
ENSRNOG00000011672 Tph1 Tryptophan 5-hydroxylase 1 NE 28 0.022
ENSRNOG00000003253 Qdpr Dihydropteridine reductase −0.94 0.033
12- vs. 28-month-old rats
ENSRNOG00000000451 RT1-Ba Rano class II histocompatibility antigen, B alpha −1.82 8.40 × 10−11
ENSRNOG00000033215 RT1-Db1 Rano class II histocompatibility antigen, D-1 beta −2.14 8.40 × 10−11
ENSRNOG00000032844 RT1-Da RT1 class II, locus Da −1.86 5.78 × 10−09
ENSRNOG00000018735 Cd74 H-2 class II histocompatibility antigen gamma −1.69 2.00 × 10−07
ENSRNOG00000019342 Sult1a1 Sulfotransferase 1A1 1.54 2.91 × 10−07
ENSRNOG00000002919 Gfap Glial fibrillary acidic protein −1.29 5.89 × 10−07
ENSRNOG00000032708 RT1-Bb Rano class II histocompatibility antigen, B-1 beta −1.83 2.44 × 10−05
ENSRNOG00000002911 Alb Serum albumin −2.19 8.80 × 10−05
ENSRNOG00000005542 Apob Apolipoprotein B-100Apolipoprotein B-48 −2.60 3.06 × 10−04
ENSRNOG00000011672 Tph1 Tryptophan 5-hydroxylase 1 NE 28 4.36 × 10−04
ENSRNOG00000030729 E9PSV0_RAT Complement component 4, gene 2 −1.78 0.004
ENSRNOG00000031230 LOC689064 Hemoglobin subunit beta-2 −1.14 0.004
ENSRNOG00000030625 Tf Signal recognition particle receptor subunit beta −0.92 0.005
ENSRNOG00000012294 Heph Hephaestin 1.11 0.007
ENSRNOG00000003253 Qdpr Dihydropteridine reductase −0.85 0.010
ENSRNOG00000000853 Aif1 Allograft inflammatory factor 1 −1.37 0.015
ENSRNOG00000008080 Hrh3 Histamine H3 receptor 1.20 0.031
ENSRNOG00000007227 RGD1306682 Similar to RIKEN cDNA 1810046 J19 (RGD1306682), mRNA −0.93 0.039
ENSRNOG00000000574 F1LTG5_RAT Uncharacterized protein −1.13 0.042
ENSRNOG00000009263 Ifi27 Interferon, alpha-inducible protein 27 −1.11 0.042

NE—not expressed (reads below 5 in all samples), 6 = 6-month-old, 12 = 12-month-old, and 28 = 28-month-old. FDR < 0.05 (fold change represents change with increasing age)