Table 2.

Toxicities at various dose levels of IP docetaxel plus S-1 during the first 2 cycles in the phase I part

Toxicity (CTCAE v. 3)	Dose of docetaxel
	35 (n = 3)		40 (n = 3)		45 (n = 3)		50 (n = 3)
	G1/2	G3/4	G1/2	G3/4	G1/2	G3/4	G1/2	G3/4
Anemia	2	0	2	0	2	0	0	0
Leukopenia	1	0	0	0	2	0	1	0
Neutropenia	1	0	0	0	1	1	2	0
Thrombocytopenia	0	0	0	0	0	0	0	0
FN	–	0	–	0	–	0	–	2
Nausea	2	0	1	0	1	0	3	0
Vomiting	0	0	0	0	0	0	0	0
Diarrhea	1	0	1	0	2	0	1	1
Abdominal pain	1	0	3	0	1	0	2	0

FN Febrile neutropenia