Table 1. In-vivo ploidy determination of interphase nuclei by image analysis/Feulgen method.
DNA index (GO/G1) | Ploidy | |
---|---|---|
Control Pot1aL/L #1 | 0.92 | Diploid |
Control Pot1aL/L #2 | 0.94 | Diploid |
Control Pot1aL/L #3 | 0.94 | Diploid |
Sprr2f-Cre; Lkb1L/L#1 | 1.03 | Diploid |
Sprr2f-Cre; Lkb1L/L#2 | 1.02 | Diploid |
Sprr2f-Cre; Lkb1L/L#3 | 0.95 | Diploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #1 | 1.86 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #2 | 2.01 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #3 | 1.37 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #4 | 1.52 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #5 | 1.66 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #6 | 1.36 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #7 | 1.54 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #8 | 1.90 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #9 | 1.41 | Aneuploid |
Sprr2f-Cre; Pot1aL/L; p53L/L #10 | 2.21 | Aneuploid |
DNA indices were determined on histologically normal endometrial epithelial cells (Pot1aL/L, controls) or malignant epithelial cells in Sprr2f-Cre; Lkb1L/L and Sprr2f-Cre; Pot1aL/L; p53L/L mice.