Linear regression analysis of genotype versus suberoylanilide hydroxamic acid-glucuronide (SAHA-G). UGT2B17 copy number variation (CNV) and SAHA-G formation rates: (a) additive model, r=0.26, P=0.062. (b) dominant model (null genotype vs. at least one copy) r=0.4, P=0.0036. UGT2B7 C802T single nucleotide polymorphism (SNP) (rs 7439366) and SAHA-G formation rates, (c) additive model, C/C=0; C/T =1; T/T=2 r=0.35, P=0.0156. (d) dominant model, C/C=0; C/T or T/T=1, r=0.30, P=0.0353.