Table 2.
Mean Estimated Glomerular Filtration Rate and Annual Change in Estimated Glomerular Filtration Rate in HIV-Infected and Matching HIV-Uninfected Women
| TDF-initiating HIV-infected women | Matched HIV-uninfected women | p-value | TDF-sparing HIV-infected women | Matched HIV-uninfected women | p-value | |
|---|---|---|---|---|---|---|
| Mean estimated GFRa after HAART initiation (years) | ||||||
| 1 year | 94.92 (92.54, 97.29) | 99.90 (98.80, 101.00) | <0.001 | 98.68 (97.08, 100.29) | 99.42 (98.27, 100.56) | 0.47 |
| 3 years | 96.12 (93.55, 98.69) | 100.48 (99.29, 101.68) | 0.003 | 97.41 (95.93, 98.89) | 98.87 (97.81, 99.93) | 0.12 |
| 5 years | 97.33 (93.69, 100.96) | 101.07 (99.36, 102.78) | 0.07 | 96.14 (94.51, 97.98) | 98.33 (97.13, 99.54) | 0.03 |
| Mean change in estimated GFR per yearb | ||||||
| 0.60 (−0.24, 1.44) | 0.29 (0.11, 0.69) | 0.51 | −0.63 (−0.96, −0.31) | −0.27 (−0.52, −0.02) | 0.08 | |
a
In ml/min/1.73 m2 (95% confidence interval).
b
In ml/min/1.73 m2 per year (95% confidence interval).
Model adjusted for baseline estimated GFR and race.