FIG. 6.

LKB1 MKO mice display normal increases in muscle glucose clearance in response to treadmill exercise. 2-deoxyglucose (2DG) clearance (mL ⋅ g⁻¹ ⋅ min⁻¹) was determined in quadriceps (A) and EDL muscle (B) from LKB1 MKO and WT mice at rest and in response to treadmill exercise at the same relative intensity. Muscle glycogen (C) (µmol ⋅ g wet wt⁻¹) and muscle lactate content (D) in quadriceps muscle from WT and LKB1 MKO mice at rest and in response to 20 min treadmill running exercise at the same relative intensity. Data are presented as means ± SEM (n = 6–13). #P < 0.05, ##P < 0.01, significantly different from rest within genotype. ND, not determined.